Basic information

Vitamin B₁₂, or cobalamin, has the largest and most complex molecule among all vitamins identified today. It is also the only vitamin to have metal ions in its composition.

Product Features

It improves the utilization of folic acid and synthesizes methionine (from homocysteine) and choline together with folic acid. It synthesizes cyanocobalamin precursors, such as methylcobalamin and cobamamide and participates in the methylation of many important compounds. When vitamin B12 is deficient, the activity of transferring methyl groups from N5-methyltetrahydrofolicacid reduces, which turns folic acid into an unusable form, thus resulting in folate deficiency. It maintains the metabolism and function of the myelin sheath of nerve. Lack of vitamin B12 can cause neurological disorders, spinal cord degeneration and serious mental symptoms. Vitamin B12 deficiency can also lead to peripheral neuritis. The early manifestations of vitamin B12 deficiency in children are abnormal mood, dull expression, and slow response, which eventually leads to anemia. It promotes the development and maturation of red blood cells. It converts methylmalonyl coenzyme A to succinyl coenzyme A, which is related to the heme synthesis, and participates in the tricarboxylic acid cycle. Vitamin B12 is also involved in the synthesis of DNA and the metabolism of fat, carbohydrate, and protein, and increases the synthesis of nucleic acid and protein.